Presentation:
One year old male intact Beagle/Pothound Mix was presented at AcaseAweek clinic for dripping of blood in urine. Eating and drinking of the patient was reported normal.
Physical Exam:
- Weight: 14.1 kg
- Temperature: 101.1°F
- Heart rate: 108 bpm
- Respiratory rate: 60 rpm
- Mucous membranes were pink and moist and CRT was less than 2 seconds.
- Popliteal lymph nodes were enlarged.
- A growth on the penis was observed as shown in the following picture:
What is your tentative diagnosis? Give differentials for your diagnosis.
What further tests you will perform to confirm your diagnosis?
How will you treat and manage this case?
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Tentative Diagnosis: Transmissible Venereal Tumor (TVT)
Differentials for Diagnosis:
(1) Squamous Cell carcinoma
(2) Cutaneous Lymphoma
Diagnostic Tests:
(1) Urinalysis: Look out for presence of abnormal cells and red blood cells
(2)Examination of impression smears or aspirate of the tumor will reveal homogeneous sheets of round to oval cells with prominent nucleoli, scant cytoplasm and multiple clear cytoplsmic vacuoles
(3) Biopsy
Treatment:
(1) Vincristine Sulfate - 0.5-0.7 mg/sqm IV once weekly beyond complete resolution of gross disease
(2) If there is partial remission or no remission at all: May give Doxorubicin (30mg/sqm IV every 3 weeks)
(3) CBC and Platelet Count before each chemotherapy treatment